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Frequency of follow-up for patients with intermediate grade colorectal adenomas

HTA: Frequency of follow-up for patients with intermediate grade colorectal adenomas

Beginning in September 2006, this study examined the effect of extending intervals between follow-up colonoscopies in people found to have intermediate adenomas, as defined by the British Society of Gastroenterology guidelines. It is using data from hospitals and from bowel cancer screening initiatives to identify groups of patients with intermediate adenomas. The risk of cancer and severe adenomas will be assessed according to the interval between examinations and the number, size and features of adenomas detected.

The study should identify whether all patients with intermediate adenomas require surveillance and whether the intervals are of the appropriate length. It should also demonstrate how many follow-up examinations are needed. Finally, it will determine whether informing patients that they need to have colonoscopy surveillance distresses them or whether they feel reassured as a result. A health economist will analyse the costs to individual patients and to the NHS and compare these with any potential benefits.

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