DMIST also called A Screening and Diagnostic Trial to Compare the Effectiveness of Two Types of Mammography in Detecting Breast Cancer in Women was carried out in the USA.
Among the objectives of the study were
- to compare the diagnostic performance of digital mammography vs screen-film mammography,in terms of sensitivity, specificity, and positive and negative predictive values, in the detection of breast cancer in women
- to determine the effects of patient characteristics, including age, lesion type, pathologic diagnosis, menopausal and hormonal status, breast density, and family history, on diagnostic accuracy of digital mammography
- to compare the effect of breast density on the diagnostic accuracy of digital mammography vs screen-film mammography
- to compare the image quality and breast radiation dose in digital vs screen-film mammography
A total of 49,500 participants (24,750 per arm) were studied and results were published in 2006-2008.
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